As a never smoker I truly wish I smoked so I could just say that's why I got this. PLoSone 2011, 11:e27547. Correlation is NOT causation. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. She wrote about a product called Thyrtophin PMG. I cried with joy when I found out there was something really wrong with me. 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. I am going to go for a walk with my dog :)). weight loss, anorexia). " The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. Brit Med J 1978, 1:210212. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? Post Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as hypothyroidism? Thyroid disease is a major public health concern worldwide. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. This discussion has been closed to comments. I do not believe in random events, of nature or otherwise. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called 'subclinical' hypothyroidism only detected via blood work. Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure, and a history of cerebrovascular disease. Note: Only a member of this blog may post a comment. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Brit Med J 1978, 1:210212. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). If people do not wish to find out all they can about their disease that is fine too. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. I am having a lot of trouble making any sense of this study. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. A distorted idea of human nature is sold when people are treated as "the market. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Non-ASPS articles which could be relevant. PMID 11836274. Yet Another Frankenfood Pandoras Box: the Majorit How Medical Science Proves that Black Is White. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. If the results show that TSH is high and T-4 is low, then the diagnosis . I invite those interested to read it and perhaps we can have a discussion on this study. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. I honestly do not know. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. Angiology 2000, 51:S65S68. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). In the U.S., the overall five-year survival rate for patients diagnosed with lung cancer is 25%, which is a 21% improvement over the . Metab.87 (2): 48999. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas. Not what people like me are saying. Asesora y Consultora Web3 para empresas. This website is for information purposes only. 2002 Feb ;25(2):106-9. I posted it to see what anyone had to add. With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. In fact, it is the high levels of T4 that make them more susceptible to cancer. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. Monaldi Arch Chest Dis 2003, 59:140145. Dr Childs guesses that patients on levothyroxine monotherapy may be more prone to cancer because they might be under-treated. It may not display this or other websites correctly. Here members can share stories, find important information and learn from the experiences of others like themselves. Also this study finds no link with breast cancer, when others have found a link. But I for one, do appreciate anything that other members forward about potential links, causes, aids to healing, whatever you can them. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. Angiology 2000, 51:S65S68. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. elevated TSH, without actually improving the overall physiological situation, nor the patients subjective experience of well being. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. The relationship between levothyroxine use and cancer risk is largely underdetermined. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. I wonder if only t3 treatments are preferable than t4 and t3 ? The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. [15] [16] There is also the more logical option of support the body's thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. Increased sleepiness. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. PMID: 23539727, [16] Alan R Gaby. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. It is worth reading. I very much appreciate the information you shared. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. Different strokes for different folks for sure! Just another excuse for keeping us on doses that are too low. PLoSone 2011, 11:e27547. Thank you for posting it, I agree we all need as much knowledge as we can get! The authors did not study whether individuals who took Synthroid actually developed lung cancer later in life. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. I have been reading Izabella Wentz. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. Thank you for bringing it to our attention. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer worldwide, according to GLOBOCAN. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Are you sure you want to block this member? If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Is Drug-Based Medicine a Form of Human Sacrifice? Acta Endocrinol 1988, 118:460464. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. Oops I have just bought my first jar of marmalade in over ten years! People read a study and think that someone like, perhaps me, is saying "it Causes lung cancer. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features.