All-age rate of deaths attributable to and associated with bacterial antimicrobial resistance by GBD region, 2019 Estimates were aggregated across drugs, accounting for the co-occurrence of resistance to multiple drugs. First, self-medication may not be effective if the patient has a virus, as antibiotics only fight bacteria. The UK government considers the threat of antibiotic resistance as seriously as: Without action to address antibiotic resistance, doctors will lose the ability to treat infections. Would you like email updates of new search results? Saving Lives, Protecting People, 2019 Antibiotic Resistance (AR) Threats Report, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Healthcare Quality Promotion (DHQP), Actions to Fight Antimicrobial Resistance, What CDC Is Doing: Investments & U.S. Action, CDC Invests in Multi-Country Projects to Help Stop Spread of Resistance, Pilot to Test for Drug-resistant Gonorrhea in Emergency Departments, CDCs Priority to Address Health Equity Issues, Protecting Patients and Healthcare Personnel from COVID-19, Experts Discuss Addressing AR After COVID-19, CDC Partners Estimate Healthcare Cost of Antimicrobial resistant Infections, Tailoring Antibiotic Treatment For Patients with Cystic Fibrosis, Tracking Antimicrobial Resistance in Kenya and Senegal, CDC Core Elements to Help Resource-limited Settings Improve Antibiotic Use, Antimicrobial Resistance: A Global Threat, Combating Antimicrobial Resistance in Vietnam, Pilot Program Accelerates Antibiotic Testing, Stop Spread of Unusual Antimicrobial Resistance, New CDC Network Established as Fungal Threat Emerges, Improving Antibiotic Prescribing with Rapid Diagnostics and Education, CDC and Partners Tackle Drug-Resistant TB in India, U.S. Department of Health & Human Services, Antimicrobial-resistant infections that require the use of second- and third-line treatments can harm patients by causing serious side effects, such as organ failure, and prolong care and recovery, sometimes for months, Many medical advances are dependent on the ability to fight infections using antibiotics, including joint replacements, organ transplants, cancer therapy, and the treatment of chronic diseases like diabetes, asthma, and rheumatoid arthritis, In some cases, these infections have no treatment options. They can support local GP practices and CCGs by providing: They can also reduce inappropriate antibiotic prescribing for flu symptoms by increasing uptake of flu vaccination. While buyer benefits from real-time prices and fair competition, sellers benefits. 00:54 Recently cleared IVD devices, including Antimicrobial Susceptibility Test (AST) devices,include: September 15, 2022: FDA cleared the Thermo Scientific Oxoid Omadacycline Disc (30 ug) OMC30 (K203336), a disk diffusion assay for in vitro susceptibility testing of omadacycline, a new antibiotic for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). The European Antimicrobial Resistance Surveillance Network (EARS-Net) is the largest publicly funded system for antimicrobial resistance (AMR) surveillance in Europe. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. He made sure that all of what we needed is delivered exactly how we wanted it. Based on consultation with and input from FDAs Centers, OPHSA routinely updates HHS on FDAs progress in meeting National Action Plan goals, objectives, and milestones. eCollection 2022. From left to right: Multi-drug resistant Salmonella enterica, kpc2 carbapenem resistance gene. September 15, 2020:Accelerate Pheno System, Accelerate PhenoTest BC Kit (K192665) a multiplexed in vitro diagnostic test utilizing both qualitative nucleic acid fluorescence in situ hybridization (FISH) identification and quantitative antimicrobial susceptibility methods directly from positive blood culture samples. antimicrobial resistance ppt 2020. The Federal Register notice includes specific questions for commenters to consider. OneClick consists of a friendly and easy-to-work-with team. Antimicrobial drugs are key in the treatment of diseases, and their use is essential to protect both human and animal health. For datasets where isolates could not be uniquely identified across pathogendrug combinations, such as some antimicrobial resistance surveillance systems, some isolates might be double counted. Before sharing sensitive information, make sure you're on a federal government site. Also see: FDA-TRACK: Progress on FDAs Support of Antimicrobial Stewardship in Veterinary Settings. AMR is a leading cause of death around the world, with the highest burdens in low-resource settings. Antimicrobial resistance has the potential to affect people at any stage of life, as well as the healthcare, veterinary, and agriculture industries. This work ultimately improves patient care and builds solutions against resistance threats. 2016;13 T Walsh reports financial support from the Bill & Melinda Gates Foundation for the BARNARDS (neonatal sepsis and mortality) study for the present manuscript. The 2021 theme, Spread Awareness, Stop Resistance, called on One Health stakeholders, policymakers, health care providers, and the general public to be Antimicrobial Resistance (AMR) Awareness champions. World Antimicrobial Awareness Week (WAAW) is celebrated from 18-24 November every year. AMR=antimicrobial resistance. This may reflect healthcare access and delivery in London, where there may be a shift from general practice prescribing to local hospitals and private healthcare. Cardiac=endocarditis and other cardiac infections. For example: If antibiotics and antifungals lose their effectiveness, then we lose the ability to treat infections and control these public health threats. Researchers gathered at McMaster University on Friday to discuss the biological, societal and political contributions to antibiotic resistant bacteria, a concern the McMaster Universitys Global Nexus has dubbed the next pandemic. Anti-microbial resistance (AMR) occurs when infection-causing pathogens like bacteria, viruses, fungi and parasites GBD=Global Burden of Diseases, Injuries, and Risk Factors Study. PMC Antimicrobial resistance wasnt discovered all at once. Interpretation: Also see from CDC: Guidance for Tecovirimat Use Under Expanded Access Investigational New Drug Protocol during 2022 U.S. Monkeypox Outbreak (September 15, 2022). We recharge ourselves with fun-filled monthly parties, rewards and recognitions, in-house sports, corporate events, and a lot more Romit Arora - Founder of OneClick IT Consultancy Pvt. September 12, 2022: Monkeypox response: FDA released additional information in publicly posted reviews supporting approval of the new drug application for tecovirimat to describe specific changes in the VP37 proteins of orthopoxviruses (e.g., vaccinia virus and monkeypox virus) that are associated with tecovirimat drug resistance. CCGs have also been asked to reduce broad-spectrum antibiotic prescribing as a percentage of the total antibiotics prescribed in primary care by 10% from each CCGs 2013 to 2014 levels. Livtencity works by preventing the activity of human cytomegalovirus enzyme pUL97, thus blocking virus replication. Thank you for taking the time to confirm your preferences. We encourage the community to share microbe samples. Although the proportion of E. coli that are resistant to antibiotics used to treat infections has remained constant, the increased incidence of bloodstream infections means that more individuals have had a significant antibiotic resistant infection. 1 One of the five CDC core actions to combat the spread of antimicrobial resistance is improving the use of antimicrobials. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Proposals should be submitted to the Broad Agency Announcement (, December 2, 2020: FDA is accepting proposals focused on research assessing the impact of extended-infusion of beta-lactam antibacterial drugs on development of beta-lactam resistance and patient outcomes. BSI=bloodstream infections. The COVID-19 pandemic pushed back years of progress made combating antimicrobial resistance (AR) in the United States. Unlock your brand's potential with our tech innovations. Claims were added to include the detection of nucleic acids from additional strains of E. coli, Citrobacter, Enterococcus, and Pseudomonas aeruginosa. Antimicrobial drugs are key in the treatment of diseases, and their use is essential to protect both human and animal health. This can then help them change their practice. Antimicrobial resistance has the potential to affect people at any stage of life, as well as the healthcare, veterinary, and agriculture industries. Antimicrobial resistance (AMR) occurs when disease-causing pathogens adapt to become able to withstand the killing or suppressing power of antimicrobial medicines. energy program manager salary; Resistance to 1+=resistance to one or more drug. Antimicrobial resistance is a phenomenon that is happening NOW and is a global problem that affects both human and animal health; Antibiotic resistance happens when bacteria stop an antibiotic from working effectively meaning some infections may We deploy the latest technologies and frameworks to build robust travel apps and portals that cater to your business model and custom requirements. 00:35. The surveillance of gonococcal antimicrobial susceptibility surveillance in Europe is essential for detecting emerging and increasing antimicrobial resistance and making quality-assured data available to inform revisions of treatment guidelines. Ad hoc Codex Intergovernmental Task Force on Antimicrobial Resistance (TFAMR), Regional Office for Europe and Central Asia, Regional Office for Latin America and the Caribbean, Regional Office for the Near East and North Africa. On this page: This includes: Also see from CDER: Combating Antibiotic Resistance. Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death. Working to ensure the labeling of antimicrobial drugs intended for use in humans contain required statements regarding appropriate use, Providing recommendations on scientifically sound clinical trial designs to evaluate human drugs to help inform appropriate use and stewardship efforts, Working with diagnostic manufacturers and academia on developing biomarkers to rapidly identify whether a patients symptoms are due to a bacterial infection, or when antibiotics can be stopped during treatment, Promoting flexible regulatory approaches to rapid identification of bacterial pathogens, thereby allowing targeted antibiotic treatment and reducing broad-spectrum antibiotic use, A partnership between the FDA, the CDC, and the U.S. Department of Agriculture (USDA), the, The FDA is funding cooperative agreements to support collection of data on antimicrobial use in U.S. animal agriculture. HHS Vulnerability Disclosure, Help They are currently also helping me with the website for my IoT products portfolio. 2022 Oct 26;8(10):1376-1379. doi: 10.1021/acscentsci.2c01070. June 3, 2022:FDA cleared the VITEK 2 AST-Gram Negative Omadacycline (0.25 - 16 g/mL) (K213931), a miniaturized, abbreviated and automated version of the classic broth dilution method to determine the minimum inhibitory concentration of omadacycline, a new antibiotic for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). Research enabling development of new vaccines against tuberculosis: Research to facilitate development of vaccines against, December 15, 2021: Beginning February 1, 2022, FDAs Center for Veterinary Medicine will accept applications for Fiscal Year (FY) 2022 to, November 22, 2021: FDA is accepting proposals focused on updating susceptibility test interpretive criteria (breakpoints). 2022 Jun 25;399(10344):2346-2347. doi: 10.1016/S0140-6736(22)00935-7. Mukwege D, Mitangala P, Byabene A, Busha E, Van Laethem Y, Vandenberg O. Lancet. One pathogen-drug combination, meticillin-resistant S aureus, caused more than 100 000 deaths attributable to AMR in 2019, while six more each caused 50 000-100 000 deaths: multidrug-resistant excluding extensively drug-resistant tuberculosis, third-generation cephalosporin-resistant E coli, carbapenem-resistant A baumannii, fluoroquinolone-resistant E coli, carbapenem-resistant K pneumoniae, and third-generation cephalosporin-resistant K pneumoniae. Hospital pharmacists should work closely with the multidisciplinary clinical team to ensure antibiotics prescribed for inpatients are appropriate for their indication and compliant with local and national guidelines and protocols. All information these cookies collect is aggregated and therefore anonymous. If no action is taken - warns the UN Ad hoc Interagency Coordinating Group on Antimicrobial Resistance who released the report drug-resistant diseases could cause 10 CVM intends to use the information collected to help develop strategies to further promote antimicrobial stewardship in companion animals. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. April 14, 2022: FDA cleared the VITEK 2 AST-Gram Negative Ciprofloxacin (0.06 - 4 g/mL) (K214023), a miniaturized, abbreviated and automated version of the classic broth dilution method to determine the minimum inhibitory concentration of ciprofloxacin, an antibiotic with updated breakpoints for testing Enterobacterales and P. aeruginosa. For years, health professionals have asked people not to self-medicate with antibiotics, especially for common illnesses such as the flu. All other authors declare no competing interests. This is an Open Access article under the CC BY 4.0 license. doi: 10.1126/sciadv.adc9566. FDA announces a new Fiscal Year 2020 funding opportunity and Request for Applications to support the collection of data on antimicrobial use in dogs and cats. June 30, 2022: FDAs Center for Veterinary Medicine released both a status update(PDF, 273 KB) on Phase I of its five-year action plan for Supporting Antimicrobial Stewardship in Veterinary Settings as well as a report(PDF, 12.8 MB) to describe some of the data that FDA and federal partners collect regarding antimicrobial sales, use, and resistance in U.S. animal agriculture and the related food chain. We rely on antibiotics to deliver modern health care, Segre says. FDA Releases Five-Year Plan for Supporting Antimicrobial Stewardship in Veterinary Settings, FDAs new efforts to advance antimicrobial stewardship in veterinary settings, FDAs efforts to foster discovery and development of new tools to fight antimicrobial-resistant infections, Vaccines and Related Biological Products Advisory Committee meeting, 2022 Public Meeting of the National Antimicrobial Resistance Monitoring System (NARMS), Virtual public workshop - Drug Development Considerations for the Prevention of Healthcare-Associated Infections, Strategies for Early-Stage Programs Developing Novel Antibacterial and Antifungal Drugs, Exploring the Potential for a Public-Private Partnership to Support the Tracking and Monitoring of Antimicrobial Use in Food-Producing Animals, Development Considerations of Antimicrobial Drugs for the Treatment of Uncomplicated Urinary Tract Infections (UTI), Science and Regulation of Bacteriophage Therapy workshop, Development Considerations of Antimicrobial Drugs for the Treatment of Gonorrhea, FDA Public Meeting on Potential Approach for Ranking of Antimicrobial Drugs According to Their Importance in Human Medicine: A Risk Management Tool for Antimicrobial Animal Drugs, Office of New Drug (OND) Research: Seeking Collaborators; Funding Opportunities Available, Virtual Public Meeting of the National Antimicrobial Resistance Monitoring System, Development Considerations of Antifungal Drugs to Address Unmet Medical Need, Developing Antifungal Drugs for the Treatment of Coccidioidomycosis (Valley Fever) Infection, Advancing Animal Models for Antibacterial Drug Development, Enhancing the Clinical Trial Enterprise for Antibacterial Drug Development, Antimicrobial Drugs Advisory Committee public meeting, Development of Antibacterial Drugs for the Treatment of Nontuberculous Mycobacterial Infection, USFDACDSCO-DIA Workshop on Global Anti-Infective Drug Development: Challenges and Opportunities, Science and Regulation of Live Microbiome-Based Products Used to Prevent, Treat, or Cure Diseases in Humans, Statement from FDA Commissioner Scott Gottlieb, M.D., on advancing the science and regulation of live microbiome-based products used to prevent, treat, or cure diseases in humans, Live Event: FDA Unveils Plan to Combat Antibiotic Resistance, Development of Non-Traditional Therapies for Bacterial Infections, Development of Inhaled Antibacterial Drugs for Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis, 2017 Scientific Meeting of the National Antimicrobial Resistance Monitoring System, FDA In Brief: Federal agencies meet to continue fight against antimicrobial resistance, Development of New Tuberculosis Drug Regimens - Scientific and Clinical Design Considerations, Bacteriophage Therapy: Scientific and Regulatory Issues, Meeting of the Antimicrobial Drugs Advisory Committee, Current State and Further Development of Animal Models of Serious Infections Caused by, Fighting antimicrobial resistance globally, National Action Plan for Combating Antibiotic-Resistant Bacteria, 2020-2025, first National Action Plan released in 2015, Consumers and general information: contact FDA, Press: contact the Office of Media Affairs. Without investment from countries in all income brackets, future generations will face the disastrous impacts of uncontrolled antimicrobial resistance. About the Antimicrobial Resistance and Infections programme. First, antimicrobial resistance is ancient and it is the expected result of the interaction of many organisms with their environment. OneClick is passionate about world-class work and believes that work-life balance is essential to delivering quality. These can multiply and spread to other people. Includes options for phone and online reporting, Press: contact the Office of Media Affairs Poultry Solution. According to the Centers for Disease Control and Prevention (PDF,148 pages), each year in the United States at least 2.8 million antibiotic-resistant infections occur, and more than 35,000 people die as a result. Download a complete set of references for this document. 2022 Nov 4;8(44):eadc9566. "Antimicrobial resistance is the ability of bacteria, viruses, fungi and parasites to change over time and no longer respond to medicines, making infections harder to treat and, in many cases, untreatable," explained Dr. Debra Goff, PharmD, an infectious disease specialist and one of 25 global experts appointed to the WHO's NAP=national AMR action plan. Many GPs admit concern about what might happen if they withhold antibiotics. November 16, 2020: MicroScan Dried Gram-Negative MIC/Combo Panels with Ceftazidime (Caz) (0.5-64 g/mL) (K202343), an abbreviated version of a broth microdilution assay to determine the minimum inhibitory concentration of Ceftazidime, a antibacterial used to treat lower respiratory tract infections, skin and skin-structure infections, bacterial septicemia, bone and joint infections, gynecologic infections, intra-abdominal infections and central nervous system infections. The world is already feeling the economic and health consequences as crucial medicines become ineffective. Global deaths (counts) attributable to and associated with bacterial antimicrobial resistance by infectious syndrome, 2019 Estimates were aggregated across drugs, accounting for the co-occurrence of resistance to multiple drugs. This report represents a summary of the results obtained from the application of the tool in six Latin American countries, from 2019 to 2021. To use penicillin as an example, this antibiotic was invented in 1941 and resistance was identified in: July 12, 2022: FDA cleared the VITEK 2 AST-Yeast Caspofungin (0.125 - 8 g/mL) (K213899), a miniaturized, abbreviated and automated version of the classic broth dilution method to determine the minimum inhibitory concentration of caspofungin, an antifungal agent with updated breakpoints for testing Candida spp. Not only for the treatment of infections such as pneumonia, meningitis and tuberculosis. Medical Royal Colleges and Health Education England. Everyone has a responsibility and a role to play in making this happen. These are: The NICE guidelines recommend that primary and secondary care healthcare professionals use these toolkits as part of their improvement of practice to assess their antibiotic prescribing rates against others. Independent Oversight and Advisory Committee, UN Ad hoc Interagency Coordinating Group on Antimicrobial Resistance, New report calls for urgent action to avert antimicrobial resistance crisis. NOAH response to final O'Neill AMR review report July 2016. Read a case study from the Royal Free Hospital explaining how a new drug chart improved antimicrobial stewardship. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. AMR=antimicrobial resistance. The toolkits also provide advice on the importance of shared decision making with patients. We also need them to avoid infections during chemotherapy, caesarean sections and other surgery. Researchers gathered at McMaster University on Friday to discuss the biological, societal and political contributions to antibiotic resistant bacteria, a concern the McMaster Universitys Global Nexus has dubbed the next pandemic. Anti-microbial resistance (AMR) occurs when infection-causing pathogens like bacteria, viruses, fungi and parasites Fukushige M, Ngo NH, Lukmanto D, Fukuda S, Ohneda O. Strong, sustained action across all sectors is vital if we are to turn back the tide of antimicrobial resistance and keep the world safe." de Kraker MEA, Stewardson AJ, Harbarth S. Will 10 million people die a year due to antimicrobial resistance by 2050? WHO Drug resistance; WPRO Drug Resistance; ; ; AMR Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen-drug combinations in Antimicrobial stewardship and microbiology laboratory teams should ensure their laboratory is reporting antimicrobial resistance data to PHE. We use some essential cookies to make this website work. ACS Cent Sci. Prescribers should ensure that they are up to date with local knowledge on the best antibiotic for each condition. International survey among beekeepers to monitor the level of knowledge and awareness on Good Beekeeping Practices (GBPs), Antimicrobial Use (AMU) and Antimicrobial Resistance (AMR). I hired Romit Arora and his team (Onceclick IT solutions) for my IoT products android and ios app development from scratch. Antimicrobial resistance is a global human and animal health concern which is influenced by the use of antimicrobial agents in both human and veterinary medicine, as well as in the plant sector. However, antimicrobials misuse in the livestock sector, aquaculture and crop production is a major concern as arisk for emergence and spread of antimicrobial resistant micro-organisms. What is antimicrobial resistance? September 22, 2022: Vaccines and Related Biological Products Advisory Committee meeting (virtual, 8:30 a.m. - 5:00 p.m. Email [emailprotected] or call 301-796-4540, An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, Antimicrobial Resistance Information from FDA, Ebola Preparedness and Response Updates from FDA, Medical Countermeasure Monitoring and Assessment, Radiological and Nuclear Emergency Preparedness Information from FDA, Smallpox Preparedness and Response Updates from FDA, Medical Countermeasures Initiative (MCMi), Centers for Disease Control and Prevention, Maximizing Benefits and Minimizing Harms from Antibiotics: Scientific, Regulatory and Clinical Considerations by Dr. Sara Cosgrove, Vaccines and Related Biological Products Advisory Committee, Thermo Scientific Oxoid Omadacycline Disc (30 ug) OMC30, Guidance for Tecovirimat Use Under Expanded Access Investigational New Drug Protocol during 2022 U.S. Monkeypox Outbreak, Employing product development program and incentives, Fast track designation, priority review, and breakthrough therapy designation, Qualified infectious disease products (QIDPs), Initial Targeted Engagement for Regulatory Advice on CBER Products (INTERACT), Encouraging the development of novel and nontraditional products, and new tools, IVD devices for detection of AMR associated with microbial pathogens, VITEK 2 AST- Gram Positive Telavancin (0.015 - g/mL), VITEK 2 AST-Yeast Caspofungin (0.125 - 8 g/mL), VITEK 2 AST-Gram Negative Omadacycline (0.25 - 16 g/mL), EPlex Blood Culture Identification Gram Negative (BCID-GN) Panel, VITEK 2 AST-Gram Negative Ciprofloxacin (0.06 - 4 g/mL), VITEK 2 AST-Yeast Fluconazole (0.5 - 64 g/mL), VITEK 2 AST-Gram Positive Linezolid (0.5 - 8 g/mL), Sensititre 18-24 Hour MIC or Breakpoint Susceptibility System with Cefiderocol in the Dilution Range of 0.03-64 g/mL, Sensititre YeastOne Susceptibility System with Voriconazole in the Dilution Range of 0.008 - 8 g/mL, VITEK 2 AST-Gram Positive Fosfomycin (8 - 256 g/mL), Thermo Scientific Oxoid Cefiderocol Disc (30ug) FDC30 (K203700), VITEK 2 AST-Gram Negative Meropenem (0.25 - 16 g/mL) (K201675), VITEK 2 AST-Gram Negative Imipenem/Relebactam (<0.25/4 - >16/4 g/mL), MicroScan MICroSTREP Plus Panels With Tetracycline (0.06-16 g/mL), MicroScan Dried Gram-Negative MIC/Combo Panels with Ceftazidime (Caz) (0.5-64 g/mL), VITEK 2 AST-Gram Negative Ceftazidime (0.5 - 32 g/mL), Accelerate Pheno System, Accelerate PhenoTest BC Kit, MicroScan Dried Gram-Negative MIC/Combo Panels with Meropenem (Mer) (0.004 - 32 g/mL), MicroScan Dried Gram Negative MIC/Combo Panels with Ciprofloxacin (Cp) (0.004 - 8 g/mL), BioFire Blood Culture Identification 2 (BCID2) Panel, VITEK 2 AST-Gram Negative Imipenem/Relebactam (0.25/4 - 16/4 g/mL), Sensititre 18-24 hour MIC or Breakpoint Susceptibility System with Cefiderocol in the dilution range of 0.03-64 g/mL, MicroScan Dried Gram-Negative MIC/Combo Panels with Levofloxacin (Lvx) (0.008 - 16 g/mL), Sensititre 20-24 hour Haemophilus influenzae/Streptococcus Pneumoniae MIC or Breakpoint Susceptibility System with Lefamulin in the dilution range of 0.008 16 g/mL, FDA authorizes marketing of diagnostic test that uses novel technology to detect MRSA bacteria, bioMerieux ETEST Delafloxacin (DFX) 0.002-32 g/mL, MicroScan Dried Gram Negative MIC/Combo Panels with Meropenem (Mer) (0.004-32 g/mL), ETEST Eravacycline (ERV) (0.002 32 g/ML), Sensititre 18-24 Hour MIC Or Breakpoint Susceptibility System With Imipenem-Relebactam In The Dilution Range Of 0.03/4-256/4 Ug/ML, Sensititre 18-24 hour MIC or Breakpoint Susceptibility System with Lefamulin in the dilution range of 0.008 16 g/mL, MTS Ampicillin-Sulbactam 0.016/0.008 256/128 g/mL, Supporting Antimicrobial Stewardship in Veterinary Settings: Goals for Fiscal Years 2019-2023, FDA-TRACK: Progress on FDAs Support of Antimicrobial Stewardship in Veterinary Settings, FDA-Recognized Antimicrobial Susceptibility Test Interpretive Criteria, Surveillance and monitoring activities and collaborations, National Antimicrobial Resistance Monitoring System, Center for Epidemiology and Animal Health, 2020 Summary Report on Antimicrobials Sold or Distributed for Use in Food-Producing Animals, 2021: Advancing Regulatory Science at FDA: Focus Areas of Regulatory Science (FARS) report, CDC-FDA Antimicrobial Resistance Isolate Bank, Database for Reference Grade Microbial Sequences, National Database of Antibiotic Resistant Organisms, Exploiting Real-World Data to Optimize the Use of Antibiotics, National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB), Safety and Efficacy of Vaccines for Tuberculosis and Other Intracellular Pathogens, Predicting How Well Vaccines Protect Against Tuberculosis, Tularemia and Other Bacteria, Improving Vaccine Manufacturing Evaluation for Bacterial Respiratory Pathogens. 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