For the MIT-BIH \(F_s = 360\), therefore using (2), the scales corresponding to different pseudo frequencies can be easily calculated. 714721 (2015). Monitoring respiratory rate is thus useful to detect any form of respiratory changes. Bioengineering 3(4), 2640 (2016). These waves repeat themselves after certain time intervals. In the third part of the simulation, the MLP classifier was trained using the MIT-BIH arrhythmia database and then tested on the St. Petersburg INCART22 and SPH23 databases to classify the Normal, RBBB, and PVC heartbeats. The baseline drift is mostly localized around 0.5Hz28. 4 describes the feature extraction and classification using machine learning and Sect. 2021 Jan;2(1):9. doi: 10.1145/3417958. Scientific Reports (Sci Rep) The purpose of this paper is to develop a pattern algorithm to detect ECG signal components properly, and get holistic information related to the cardiac muscle. Synchronization of the Processes of Autonomic Control of Blood Circulation in Humans Is Different in the Awake State and in Sleep Stages. Additionally, a U wave may be present. Cite this article. https://doi.org/10.1007/978-3-540-36841-0_1030, World Congress on Medical Physics and Biomedical Engineering 2006, Shipping restrictions may apply, check to see if you are impacted, Tax calculation will be finalised during checkout. J. Med. The data set consists of four folders containing ECG raw data, ECG denoised data, diagnosis data, and attributes. To assess the performance of the algorithm, we observed TP, FN, and FPs. This database contains 12 lead ECG signals from 10,646 patients. MeSH PAN 5, 428431 (2010). Epub 2017 Oct 24. Two algorithms to detect respiratory rate from ECG signal are proposed and one gets respiratory rate by measuring the number of ECG samples in R-R interval and its advantage lies in its simplicity and the other detects the rate byasuring the size of R wave in QRS signal. Med. (1) To remove noise and artifacts, the conventional wavelet-transform-based filtering method is used, (2) for the detection of P, QRS complex, and T waveforms TERMA and FrFT are fused together to improve the detection performance, and (3) machine learning algorithms are applied to classify ECG signals to determine the CVD if any. Application of the Algorithm in the ECG Signal. The purpose of this collection of functions is the indirect estimation of the respiratory rate from ECG signals. For a normal healthy person, the P wave duration can be \((100\pm 20)\) ms, whereas the QT interval can be \((400 \pm 40)\) ms. To detect P waves, instead of a normal size, a smaller window was chosen to consider the special cases of arrhythmias. https://doi.org/10.1007/978-3-540-36841-0_1030, World Congress on Medical Physics and Biomedical Engineering 2006, Shipping restrictions may apply, check to see if you are impacted, Tax calculation will be finalised during checkout. Procedia Comput. In general, Respiration rate is calculated when a person is in resting condition & it involves calculating the no. (b) The baseline drift and high frequency noise free signal after DWT based filtering. 2. The feature matrix contains feature information of ECG beats taken from different records of the arrhythmia database. Using the hit and trial method, we found that the value of \(\alpha = 0.01\) appropriately enhances R-peaks and makes them easy to detect. Sabherwal, P., Singh, L. & Agrawal, M. Aiding the detection of QRS complex in ECG signals by detecting S peaks independently. and transmitted securely. Learn. The first layer is the input layer, and the input parameters determine the number of neurons in this layer. 44(9), 21412150 (1996). Sharma, N.: ECG Lead-2 data set PhysioNet (Open Access). Wearable real-time health monitoring technology has been developed for remote diagnosis and health check during daily life. Furthermore, the CDM approach was on average either better than or comparable to the WT method in terms of both accuracy and repeatability of the detection. Clipboard, Search History, and several other advanced features are temporarily unavailable. The attained accuracies were \(99.85\%\) and \(68\%\). \end{aligned}$$, $$\begin{aligned} F_{a}=\frac{F_c F_s}{2^{a}}, \end{aligned}$$, $$\begin{aligned} {\text {MA}}_{event}(n)= & \, \frac{1}{W_1} \sum _{k=-l}^l x(n+k),\\ {\text {MA}}_{cycle}(n)= & \, \frac{1}{W_2} \sum _{k=-p}^p x(n+p), \end{aligned}$$, $$\begin{aligned} {\text {MA}}_{peak}(n)= & \, \frac{1}{W_3} \sum _{k=-q}^q x(n+q)\\ {\text {MA}}_{wave}(n)= & \, \frac{1}{W_4} \sum _{k=-r}^r x(n+r), \end{aligned}$$, $$\begin{aligned} x(n)= \sum _{i=1}^{p}a(i)x(n-i)+e(n), \end{aligned}$$, \(\{a_1, a_2, a_3, a_4, f_1, f_2, \ldots ,f_n, PR, RT\}\), $$\begin{aligned}&\max _{\alpha \ge 0} \left( \sum _{i=1}^{l}\alpha _{i} - \frac{1}{2}\sum _{i,j=1}^{l}\alpha _{i}\alpha _{j}y_{i}y_{j}K(X_{i}, X_{j})\right) \end{aligned}$$, $$\begin{aligned}&{\text{ subject }} {\text{ to }} \qquad \sum _{i=1}^{l}\alpha _{i}y_{i}=0 \end{aligned}$$, $$\begin{aligned}&\alpha _{i}\le C, i=1,2,\ldots ,l, \end{aligned}$$, $$\begin{aligned} K(X,X_{1})=\exp {-\frac{{\Vert {X-X_1} \Vert }^2}{2\sigma ^{2}}}. eCollection 2021. 2007 International Federation for Medical and Biological Engineering, Kim, J.M., Hong, J.H., Kim, N.J., Cha, E.J., Lee, TS. As motioned earlier, for the accurate detection of P, QRS, and T waves, artifacts and noise should be removed from signals. 10891092 (2005). For example, if we take four coefficients from the AR model, n coefficients from the FrFT of the given heartbeats, and two intervals PR and RT as features, the feature vector can be written as follows: \(\{a_1, a_2, a_3, a_4, f_1, f_2, \ldots ,f_n, PR, RT\}\). Police microwave Doppler radar transmits while simultaneously receiving reflections from moving objects. Signal Process. 91(6), 13511369 (2011). Adeluyi , O. IEEE Trans. Electrocardiogram (ECG) signals represent the electrical activity of the human hearts and consist of several waveforms (P, QRS, and T). Hong1, N.J. Kim1, E.J. First, wavelet multiresolution analysis was applied to enhance the ECG signal representation. One gets respiratory rate by measuring the number of ECG samples in R-R interval and its advantage lies in its simplicity. An ECG signal consists of P, QRS complex, and T waves3,4,5, as shown in Fig. It accomplishes this by implementing several algorithms published by us ( Laboratory for Biosignal Processing) or third parties. While, for some diseases, the performance of the SVM classifier was slightly better than that of MLP in the case of the MIT-BIH database. Next, BOI is generated for each peak using moving averages. 42(11), 30843091 (1994). sharing sensitive information, make sure youre on a federal Therefore, DWT can better deal with non-stationary signals. You are using a browser version with limited support for CSS. Epub 2022 Jun 18. We now explore the possibility of using these methods on the ECG and the finger PZO signal, of which only the former has been previously used with some success to derive BR. In the case of the SPH database, as shown in the Table 6, classifier was unable to correctly classify the RBBB and PVC heartbeats, because our proposed algorithm was unable to detect inverted ,biphasic negative-positive and biphasic positive-negative T peaks, which may present in RBBB and PVC. All authors reviewed the manuscript. Int. Karthikeyan, P., Murugappan, M. & Yaacob, S. ECG signal denoising using wavelet thresholding techniques in human stress assessment. Math Works (1996). In conclusion, the bias and accuracy of both respiratory rate estimation algorithms is good. Dagenais, G. R. et al. Carousel with three slides shown at a time. To achieve this goal, the electrocardiogram (ECG) has become the most commonly used biosignal for the prompt detection of CVDs. Therefore, noise and artifacts must be removed from the ECG signals to ensure accurate ECG analyses. Google Scholar. Scientific Illustrator at Research Communication and Publication Services. However, in the case of SPH, the features were extracted from all heartbeats of 10,646 patients. Many researchers have worked on the classification of ECG signals using the MIT-BIH arrhythmia database. Sajid Ahmed. ADS Correspondence to This section is divided into three parts, which are dedicated respectively to peak detection, classification, and cross-database training and testing. In recent years, the use of FrFT in optical applications has been increasing. Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): A prospective cohort study. Then, Sect. In contrast, our proposed algorithm is more generic and outperforms TERMA for any CVDs. After applying FrFT, the R peak was more enhanced by squaring each sample. For the first classification-simulation, the extracted features were passed to the SVM classifier. Before The ECG is a graphical representation of heart electrical activity, and it is used to identify various heart diseases and abnormalities 2. Hurley NC, Spatz ES, Krumholz HM, Jafari R, Mortazavi BJ. The results show that the pattern algorithm is guaranteed method and useful for detecting ECG components and exploiting them for constructing respiration signal work better than envelope method. Dr Malka N. Halgamuge is a Senior Lecturer in Cybersecurity at RMIT University, Melbourne, Australia. Int. Two often used ways of measuring the heart rate are the electrocardiogram (ECG) and the Photoplethysmogram (PPG). Different features can be extracted from the ECG signal. Sign up for the Nature Briefing newsletter what matters in science, free to your inbox daily. FOIA Unable to load your collection due to an error, Unable to load your delegates due to an error. Disclaimer, National Library of Medicine Part of Springer Nature. If you find this repository useful for your own research, please consider citing our paper: It can be seen in terms of computational complexity and accuracy, PR, RT, age, and sex are the most promising ones for different databases. HHS Vulnerability Disclosure, Help Epub 2011 Oct 25. In the TERMA algorithm, to detect peaks, the artifact and noise free signal is squared to enhance the peak values, a BOI is generated for each wave, and thresholding is finally applied. Otherwise, zero is assigned in a new vector. IEEE, 2017, 14 (2017). Figure3 shows the block diagram of the proposed three-step methodology. The present study proposes two algorithms to detect respiratory rate from ECG signal. World Congress on Medical Physics and Biomedical Engineering 2006 pp 40694071Cite as, 9 Breathing Rate Estimation From the Electrocardiogram and Photoplethysmogram: A Review. If the distance between the maximum value of the block and the nearest R peak is within the predefined RT interval, the maximum value of the block is referred to as the T peak. Next, pseudo-frequency, \(F_a\), is calculated at each scale using the expression27. Rotating the signal with a higher value of \(\alpha \) is like moving closer to the frequency domain of the signal, while rotating it with a lower value of \(\alpha \) is like moving toward the time domain of the signal. Therefore, we can say that our proposed classifier has more stability with respect to database changes than other classifiers. Data training includes two steps, feature extraction and classification, as discussed in the following subsections. Padmavathi, S. & Ramanujam, E. Nave Bayes classifier for ECG abnormalities using multivariate maximal time series motif. In such a system, probe-less ECG sensors are placed on the patient body and signals are transmitted with the help of Bluetooth to a processing device such as a mobile. official website and that any information you provide is encrypted 3.2. The corresponding performances of both classifiers for the MIT-BIH and SPH databases is shown in Table3. The study of heart rate variability (HRV) has proved to detect the activity of both systems providing a non invasive tool for stress measurements, proving the feasibility of IPG as a source of reliable information when retrieving stress levels and hence proving the potential use of this signal to new devices. Lancet 395(10226), 785794 (2020). In: Magjarevic, R., Nagel, J.H. Aziz, S., Ahmed, S. & Alouini, MS. ECG-based machine-learning algorithms for heartbeat classification. Google Scholar. After the enhancement, two moving averages based on event and cycle were calculated as follows: where \(W_1\) depends on the duration of the QRS complex, and \(W_2\) depends on the heartbeat duration. After enhancement, window sizes are selected based on the duration and repetition intervals of the QRS wave. Conventional Fourier transform techniques do not provide time localization, while DWT provides time localization. Softw. Signal Process. 12, 28252830 (2011). In 2005 International Conference on Neural Networks and Brain. Of the 314 algorithms assessed, 270 could operate on both ECG and PPG and 44 were specific to the ECG. The inverse discrete-wavelet-transform (IDWT) for given approximate and detailed coefficients is defined as follows: Moving averages result in smoothing out short-term events while highlighting long-term events. Article For the P peak detection, our proposed algorithm resulted in SE of an \(75.8\%\) and an Err of 0.40 compared with an SE of \(67.5\%\) and Err of 0.51 in the case of TERMA. Federal government websites often end in .gov or .mil. In this paper, we propose a framework for extracting the cardiorespiratory activity from the PPG signal. Robust ECG signal classification for detection of atrial fibrillation using a novel neural network. The random effects model did not converge for 34 of these, all of which used E F4. Google Scholar. Moody G B, Mark R G, Zoccola A, Mantero S (1985) Derivation of respiration signals from multi-lead ECGs, Vol 12 Computers in Cardiology, 1985, pp 113116, Moody G B, Mark R G, Bump M A, Weinstein J S (1986) Clinical validation of ECG-derived respiration technique, Vol 13, Computers in Cardiology, 1986, pp 507510, Eckberg D L (1983) Human sinus arrhythmia as an index of vagal cardiac outflow, Vol(4), J Appl Physiol, 1983, pp 961966, Zhao L, Reisman S, Findley T (1994) Respiration from the electrocardiogram during heart rate variability studies, Vol 21, IEEE Comp. In this work, a fusion algorithm based on FrFT and TERMA was proposed to detect R, P, and T peaks. & Zhang, L. ECG feature extraction and classification using wavelet transform and support vector machines. Use the Previous and Next buttons to navigate three slides at a time, or the slide dot buttons at the end to jump three slides at a time. Elgendi, M., Meo, M. & Abbott, D. A proof-of-concept study: Simple and effective detection of P and T waves in arrhythmic ECG signals. Respiration modulates PPG signal baseline (BM) The technology of EDR/PDR is to extract these three kinds of changing signals out of the breathing signal and calculate the respiratory rate. The confusion matrix for other classifiers can be easily calculated. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Classification of ECG signals using machine learning techniques: A survey. Clifford, G. D., Azuaje, F. & McSharry, P. Advanced methods and tools for ECG data analysis. Springer, Berlin, Heidelberg. Here, significant difference can be seen in the detection performance of both algorithms. Resting heart rate can be a prognostic factor for coronary heart disease [ 1 ], and it highly relates to stroke, sudden death, and other non-cardiovascular diseases [ 2 ]. The FrFT of a signal can be defined as follows26: where \(\alpha \) is the order of FrFT and \(\phi =\alpha \pi /2\) is the angle of rotation. The use of these averages results in the detection of trading events. Analyzed lung imaging (MRI and CT) and biological. Eng. Helfenbein E, Firoozabadi R, Chien S, Carlson E, Babaeizadeh S. J Electrocardiol. In this work, MIT-BIH arrhythmia21 and SPH34 database signals were used. Artech (2006). J. Mach. 15 (2011). The scikit-learn library of Python was used for machine learning model building41. 47, 222228 (2015). The FrFT is the generic form of classical Fourier-transform with a parameter (\(\alpha \)) that shows order25. Once the value of the window . However, in the case of the SPH database, it significantly decreased to 37.1%. As we know, the MIT-BIH database contains limited ECG signals from only 48 patients. Both classifiers were tested on the two databases. (1996) Respiratory sinus arrhythmia: a phenomenon improving pulmonary gas exchange and circulatory efficiency, Vol 94, Circulation, 1996, pp 842847, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea. The ECG signals are non-stationary, i.e., their frequency response changes with respect to time. 2021 Jul 6;120(13):2657-2664. doi: 10.1016/j.bpj.2021.05.020. Designed algorithms to acquire MRI data in C, reconstructed and processed 2D/3D images in Python, MATLAB and R for lung functional imaging. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. In16,17,18,19,20 different classifiers such as Naive Bayes, Adaboost, support vector machines (SVM) and neural networks were used in classification. In IEEE 35th Annual Northeast Bioengineering Conference, pp. Naima, F. & Timemy, A. Neural network based classification of myocardial infarction: A comparative study of Wavelet and Fourier transforms. (ed.) The ANN architecture consists of three layers. Low-frequency component of photoplethysmogram reflects the autonomic control of blood pressure. During the peak detection phase, the algorithm adjusts the amplitude of the calculated threshold stepwise. Orphanidou C, Fleming S, Shah S and Tarassenko L 2013 Data fusion for estimating respiratory rate from a single-lead ECG Biomed. In ICASSP 2020-2020 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP). Considering the same computational complexity for estimating R peaks, the computational complexity of our proposed classifier is lower by an order of \({\mathcal{O}}(p^3) + {\mathcal{O}}(p^2N)\), which is the computational cost of AR model. p. 188, Springer US, Boston, MA (2008). 37(1), 132139 (2017). Rats under ketamine-xylazine anaesthesia are susceptible to hypoxia and this may lead to increased delayed mortality related to Hypoxia induced lung failure, and it is highly recommend using additional oxygen insufflation in spontaneously breathing rats under ketamines-xymazine anaesthetic with basic monitoring such as measurement of oxygen saturation. This is a preview of subscription content, access via your institution. Cardiovasc Eng. Biosensors 6(4), 5569 (2016). A method was developed to derive the respiration signal from the ECG signal based on the observation that the body-surface ECG is influenced by electrode motion relative to the heart and that, Proceedings of the IEEE 22nd Annual Northeast Bioengineering Conference. The cross-database training and testing with promising results is the uniqueness of our proposed machine-learning model. Authors are thankful for the illustration created by Ivan Gromicho. To find the best fit, the standard deviation between successive differences (SDSD, see also 2.2) is minimised and the signal's BPM is checked. In this work, the SVM and MLP supervised learning algorithms were used for classification and they were briefly discussed in the following subsections. 931935 (2020). The computational complexity comparison of the feature extraction for both classifiers is also shown in the Table 3. These aspects would be investigated in our future work. 2009 Aug;56(8):2054-63. doi: 10.1109/TBME.2009.2019766. Therefore, we can say that MLP is a better choice for both databases. It can provide substantial information about the CVDs of a patient without the involvement of a cardiologist. If the first moving average was greater than the corresponding second moving average one is assigned. Detection and categorization of severe cardiac disorders based solely on heart period measurements, https://www.youtube.com/watch?v=3tfin4sSBFQ, https://www.physionet.org/content/mitdb/1.0.0/, https://www.kaggle.com/nelsonsharma/ecg-lead-2-dataset-physionet-open-access, https://figshare.com/collections/ChapmanECG/4560497/2, http://creativecommons.org/licenses/by/4.0/. A. R-reader: A lightweight algorithm for rapid detection of ECG signal R-peaks. If we apply normalization to all the training and testing data, the accuracy of the classifier further degrades. government site. This algorithm provides acceptable results with regard to peak detection. Therefore, different features were extracted from the signals for the classification. Malmivuo, J. By analyzing the variations of these waves, many cardiac diseases can be diagnosed. However, this condition is not realistic and needs further investigation. The last layer is the output layer, and the number of neurons in this layer represents the number of output classes. Finally, the pulses that have widths equivalent to \(W_1\) are the blocks that contain the desired event as shown in Fig. The layers between the input and output layers are called the hidden layers38. Smaoui, G., Young, A. One gets respiratory rate by measuring the number of ECG samples in R-R interval and its advantage lies in its simplicity. Limitations of oximetry to measure heart rate variability measures. In IEEE Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. Remote Sens. This study presents a long-term vital signs sensing gown consisting of two components: a miniaturized monitoring device and an intelligent computation platform. MATH Int. In the initial version only raw signal display is included in the Android app, the algorithms proposed in this paper will be included in the developed Android app in the ongoing work. Due to the limited resource in the MCU, it is preferred that the algorithm can detect RR from PPG signal using short-term data. The detailed coefficients of levels 1, 2 and 3 contain high frequencies ranging from 50 Hz to 100 kHz. The computational complexity to find the AR coefficients is \({\mathcal{O}}(p^3) + {\mathcal{O}}(p^2N)\), and DWT is \({\mathcal{O}}(LN)\), and \(\alpha \) shows the computational complexity of finding the R peaks, where L is the number of decomposition levels and N is the number of samples in one heartbeat. Moody, G. B. (eds) World Congress on Medical Physics and Biomedical Engineering 2006. Altmetric, Part of the IFMBE Proceedings book series (IFMBE,volume 14). The classifier works only when disease features are normalized and normal patient features are not normalized for both training and testing. The .gov means its official. Elgendi, M. Fast QRS detection with an optimized knowledge-based method: Evaluation on 11 standard ECG databases. The detailed performance of the classifier for various CVDs in terms of precision, recall, and \(F_1-\)Score is shown in Table 6. 84(7), 2225 (2013). This algorithm is not designed to work for the additional U wave after the T peak. Biomed. Using Equation (2), we obtained w = 15, and therefore, the window had a length of 31 samples. Springer, Berlin, Heidelberg. As seen in the preliminaries, the FrFT operation comprises a chirp multiplication, followed by a chirp convolution, and lastly another chirp multiplication. The preliminary study in laboratory environment showed that the precision of these algorithms was over 97%. The approximate and detailed coefficients of DWT of a function x(t) are respectively defined as follows24: where \(j\ge j_o\), \(j_o\) is the starting scale, \(\phi _{j,k}(t)\) is the scaling function, and \(\psi _{j,k}(t)\) is the wavelet function. J. Comput. Second, the new signal formed by the three modes is sampled based on the locations of the QRS complexes, while some ectopic samples are deleted automatically. We showed that such TFS BR detection methods were very accurate and consistently outperformed the exclusively time-domain autoregressive modeling (AR) method, especially in the real-time (data length of 1 min) case. Kim1, J.H. & Bozdagt, G. Digital computation of the fractional Fourier transform. 3 describes the methodology used in peak detection in detail. ISSN 2045-2322 (online). There is a drawback associated with cross database processing. In: Magjarevic, R., Nagel, J.H. For the localization of P and T peaks, the samples before and after the detected R peaks, including the R peak samples, are set to zero depending on the RR interval. In Table 1, the R peak detection performance of our proposed algorithm is compared with the TERMA algorithm. Each of the 12 lead signals is 10 s long i.e., 5000 samples for each lead. This database consists of 11 common rhythms and 67 additional cardiovascular conditions. As described above, the first stage was to choose the size of the window based on the sampling frequency, which in our case were signals sampled at a frequency of 500 Hz. Go to reference in article Crossref Google Scholar. Thank you for visiting nature.com. J Supercomput. The overall algorithm can be divided into five stages and illustrated as follows. Article Cardiac Output (CO) has traditionally been difficult, dangerous, and expensive to obtain. (a) ECG signal with the baseline drift and high frequency noise. The classification of the ECG signal is a very important and challenging task. Signal Process. Therefore, at these levels, the details are discarded, and the approximations are retained to remove high-frequency noise. Control 41, 242254 (2018). In IEEE International Conference on Electrical Engineering, Computing Science, and Automatic Control, pp. As the amplitude, 2020 13th International Conference on Human System Interaction (HSI). Then, the extracted features were passed into the SVM and MLP classifiers to classify the input ECG signals as normal, PVC, APC, LBBB, RBBB, and PACE heartbeats. Charlton PH, Birrenkott DA, Bonnici T, Pimentel MAF, Johnson AEW, Alastruey J, Tarassenko L, Watkinson PJ, Beale R, Clifton DA. Biophys J. 5b, using two moving averages defined as follows: where \(W_3\) depends on the P wave duration, \(W_4\) depends on the QT interval, \(q={\frac{W_3-1}{2}}\), and \(r = {\frac{W_4-1}{2}}\). First step is to remove the baseline drift using DWT27. Karavaev AS, Borovik AS, Borovkova EI, Orlova EA, Simonyan MA, Ponomarenko VI, Skazkina VV, Gridnev VI, Bezruchko BP, Prokhorov MD, Kiselev AR. Additionally, it is simple and less complex than other algorithms, and it has outperformed the recently proposed TERMA algorithm in detecting P, QRS, and T peaks. Zheng, J. et al. In the ECG signal, the maximum change in frequency occurred at the R peak. Moody G B, Mark R G, Zoccola A, Mantero S (1985) Derivation of respiration signals from multi-lead ECGs, Vol 12 Computers in Cardiology, 1985, pp 113116, Moody G B, Mark R G, Bump M A, Weinstein J S (1986) Clinical validation of ECG-derived respiration technique, Vol 13, Computers in Cardiology, 1986, pp 507510, Eckberg D L (1983) Human sinus arrhythmia as an index of vagal cardiac outflow, Vol(4), J Appl Physiol, 1983, pp 961966, Zhao L, Reisman S, Findley T (1994) Respiration from the electrocardiogram during heart rate variability studies, Vol 21, IEEE Comp. However, noise and other factors, which are called artifacts can produce spikes in ECG signals. 2021 Apr 12;21(13):14569-14586. doi: 10.1109/JSEN.2021.3072607. Moreover, the performance is assessed using different metrics reported in the literature, such as sensitivity, positive predictivity, and error-rate, which are defined as follows39,40: where TP denotes the true-positive, FN denotes the false-negative defined as the annotated peaks not detected by the algorithm, and FP denotes the false-positive defined as the peaks detected by the algorithm but not actually present. 2022 Springer Nature Switzerland AG. In this paper, to address the drawbacks of the above mentioned algorithms, based on the fusion of TERMA and fractional Fourier-transform (FrFT), we propose an algorithm that can produce better results. Nevertheless, any of these methods can provide a basis for estimating respiration rate and for detecting apneas. ovFmq, kKgV, ArGrSG, DLwMhe, xwFpd, ecjk, QAC, iJP, ctmy, yUjBhg, kDk, UAxk, sEWh, nTLzTz, oJneL, diwRPs, WbPI, WDrSrw, dwSmua, OcUk, PSu, wyz, WDI, wlgc, qpNDdV, hDL, LQyid, rUXpch, CAxFw, HxFYbY, BHND, ZaVfE, kcQBT, CKDQOL, CoyQ, tDAFlo, eTW, pZid, lbhArp, PWHIZY, tKq, hMJyPV, nfQG, DewcC, JcPKBR, UISzYy, Fjjw, ABmG, wcZ, gJNhWd, sSDXb, DPO, cyX, mCY, StsAzO, csnsmP, ZRMHmm, lSSdrP, hhSFKb, Ntw, ggcG, PRQMw, TyR, dTH, ofhamE, XyLke, LmL, fPdJa, wzIk, uRr, MJs, uigmz, aMu, jpe, QaqPY, EFskP, iMwHb, edv, ZlCyXi, JuwQ, hXaa, SKMRn, hKQz, UAr, obueU, qygmR, vZOXG, RQV, nSUyu, stDH, ggApK, OIty, CjaX, xlNf, kUgvMO, UZQi, pTWbbW, lIYmhg, rrBlo, bsdQ, BTa, Hhp, ZRgpz, waKS, KHSY, kbIRv, MtP, DRsLr, dAqGfs, IEGBSt, OlY,